Voltage-Gated Sodium Ion Channel Activation

Preferred Label : Voltage-Gated Sodium Ion Channel Activation;

NCIt definition : A process that involves detection of alteration to the voltage across a membrane, and results in opening of the channel to become selectively permeable to sodium ions. This interaction plays a key role in conduction of nerve impulses throughout the central and peripheral nervous systems. Deficiencies in this process may result in various channelopathies, featuring epilepsy, seizures and paralysis.;

NCIt note : Deficiencies in this process may result in various channelopathies, featuring epilepsy, seizures and paralysis.;

Details

Origin ID

C88551;

UMLS CUI

C2982037;

Automatic exact mappings (from CISMeF team)
- Voltage-Gated sodium channel agonists [MeSH Descriptor]
- voltage-gated sodium channel activity [GO term]
Semantic type(s)
- Phenomenon or Process [UMLS semantic type]
biological_process_involves_gene_product
- Sodium Channel Protein Type 1 Subunit Alpha [NCIt concept]
- Sodium Channel Protein Type 11 Subunit Alpha [NCIt concept]
- Sodium Channel Protein Type 2 Subunit Alpha [NCIt concept]
- Sodium Channel Protein Type 4 Subunit Alpha [NCIt concept]
- Sodium Channel Protein Type 5 Subunit Alpha [NCIt concept]
- Sodium Channel Protein Type 8 Subunit Alpha [NCIt concept]
- Sodium Channel Protein Type 9 Subunit Alpha [NCIt concept]
biological_process_is_part_of_process
- Biochemical Process [NCIt concept]
process_involves_gene
- SCN11A Gene [NCIt concept]
- SCN11A wt Allele [NCIt concept]
- SCN1A Gene [NCIt concept]
- SCN1A wt Allele [NCIt concept]
- SCN2A Gene [NCIt concept]
- SCN2A wt Allele [NCIt concept]
- SCN4A Gene [NCIt concept]
- SCN4A wt Allele [NCIt concept]
- SCN5A Gene [NCIt concept]
- SCN5A wt Allele [NCIt concept]
- SCN8A Gene [NCIt concept]
- SCN8A wt Allele [NCIt concept]
- SCN9A Gene [NCIt concept]
- SCN9A wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients