Sodium Channel Protein Type 8 Subunit Alpha

Preferred Label : Sodium Channel Protein Type 8 Subunit Alpha;

NCIt synonyms : Voltage-Gated Sodium Channel Type VIII Alpha Protein; Sodium Channel Protein Type VIII Subunit Alpha; Sodium Voltage-Gated Channel Alpha Subunit 8; Voltage-Gated Sodium Channel Alpha Subunit Nav1.6; SCN8A;

NCIt definition : Sodium channel protein type 8 subunit alpha (1980 aa, 225 kDa) is encoded by the human SCN8A gene. This protein may be involved in the formation of podosomes and invadopodia by macrophages and in the establishment of an active potential gradient in neurons.;

Details

Origin ID

C190833;

UMLS CUI

C1434620;

OMIM relation
- Sodium voltage-gated channel, alpha subunit 8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SCN8A protein, human [MeSH Supplementary Concept]
- SCN8A protein, human [MeSH concept]
gene_encodes_gene_product
- Ion Channel Protein Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- SCN8A Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Hippocampus [NCIt concept]
gene_product_has_associated_anatomy
- Axon [NCIt concept]
- Cellular Membrane [NCIt concept]
- Ion Channel [NCIt concept]
- Macrophage [NCIt concept]
- Monocyte [NCIt concept]
- Secretory Vesicle [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Surface Extension [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]
- Voltage-Gated Sodium Ion Channel Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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