NAV1.5 Voltage-Gated sodium channel

Preferred Label : NAV1.5 Voltage-Gated sodium channel;

MeSH definition : A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of CARDIOMYOCYTES. Defects in the SCN5A gene, which codes for the alpha subunit of this sodium channel, are associated with a variety of CARDIAC DISEASES that result from loss of sodium channel function.;

MeSH synonym : NAV1.5 voltage gated sodium channel; type 5 Voltage-Gated sodium channel; type 5 voltage gated sodium channel; Voltage-Gated sodium channel type 5; voltage gated sodium channel type 5;

MeSH hyponym : Voltage-Gated sodium channel type 5 subunit alpha; Voltage Gated Sodium Channel Type 5 Subunit alpha; SCN5A Sodium Channel alpha Subunit; Voltage-Gated Na Channel Na(v)1.5a; Sodium Channel Protein Type 5 Subunit alpha; Sodium Channel, Voltage-Gated, Type V, alpha Subunit;

Is substance : O;

Details

Origin ID

D062554;

UMLS CUI

C3494335;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Record concept(s)
- NAV1.5 Voltage-Gated sodium channel [MeSH concept]
- Voltage-Gated sodium channel type 5 subunit alpha [MeSH concept]
Related MeSH Supplementary Concept(s)
- SCN5A protein, human [MeSH Supplementary Concept]
- Scn5a protein, mouse [MeSH Supplementary Concept]
- Scn5a protein, rat [MeSH Supplementary Concept]
- ventricular fibrillation, paroxysmal familial, 1 [MeSH Supplementary Concept]
Related MeSH term(s)
- Voltage-Gated sodium channel agonists [MeSH Descriptor]
- Voltage-Gated sodium channel blockers [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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