GDNF Family Receptor Alpha-Like

Preferred Label : GDNF Family Receptor Alpha-Like;

NCIt synonyms : GDNF Family Receptor Alpha Like; GDNF Family Receptor Alpha-Like Protein; GFRAL; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha-Like; IVFI9356;

NCIt definition : GDNF family receptor alpha-like (394 aa, 45 kDa) is encoded by the human GFRAL gene. This protein plays a role in growth/differentiation factor 15 binding and downstream signaling in the brainstem.;

NCI Metathesaurus CUI : CL1405502;

Details

Origin ID

C171391;

UMLS CUI

C5400890;

OMIM relation
- Gdnf family receptor alpha-like protein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- GFRAL Gene [NCIt concept]
- Growth Factor Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_expressed_in_tissue
- Brain Stem [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cell Survival [NCIt concept]
- Ligand Binding [NCIt concept]
- Nervous System Development [NCIt concept]
- Receptor Signaling [NCIt concept]
is_target
- Anti-GFRAL Monoclonal Antibody NGM120 [NCIt concept]

Keyword's position in hierarchy(ies) :

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