Oxysterols Receptor LXR-Alpha

Preferred Label : Oxysterols Receptor LXR-Alpha;

NCIt synonyms : Liver X Receptor-Alpha; Liver X Nuclear Receptor Alpha; Nuclear Receptor Subfamily 1 Group H Member 3; Liver X Receptor Alpha; NR1H3;

NCIt definition : Oxysterols receptor LXR-alpha (447 aa, 50 kDa) is encoded by the human NR1H3 gene. This protein is involved in transcriptional regulation and cholesterol homeostasis.;

Details

Origin ID

C132115;

UMLS CUI

C4308246;

Automatic exact mappings (from CISMeF team)
- Liver X Receptor Alpha [MeSH concept]
- Liver X Receptors [MeSH Descriptor]
- Nuclear receptor subfamily 1, group H, member 3 [ORDO Gene]
- Nuclear receptor subfamily 1, group h, member 3 [OMIM gene]
- nuclear receptor subfamily 1 group H member 3 [HGNC gene]
OMIM relation
- Nuclear receptor subfamily 1, group h, member 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- NR1H3 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- NR1H3 Gene [NCIt concept]
- Nuclear Receptor Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Hormone Receptor [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Nuclear Hormone Receptor Superfamily [NCIt concept]
gene_product_has_structural_domain_or_motif
- Hormone Receptor DNA-Binding Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Insulin Resistance Pathway [NCIt concept]
- Lipid Metabolism and Toxicity Pathway [NCIt concept]
- PPAR Pathway [NCIt concept]
- PPAR-alpha Gene Regulation Pathway [NCIt concept]
- RXR and RAR Heterodimerization with Other Nuclear Receptor Signaling Pathway [NCIt concept]
- Regulation of Cholesterol Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- Cholesterol Homeostasis [NCIt concept]
- DNA Binding [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Maturation [NCIt concept]
- Pattern Formation [NCIt concept]
- Receptor Signaling [NCIt concept]
- Steroid Metabolic Process [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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