" /> High Affinity Nerve Growth Factor Receptor Isoform TrkA-III - CISMeF





Preferred Label : High Affinity Nerve Growth Factor Receptor Isoform TrkA-III;

NCIt synonyms : TrkAIII; Tyrosine Kinase Receptor A Isoform TrkA-III; Tyrosine Kinase Receptor Isoform TrkA-III; Nerve Growth Factor Receptor Type 1 Isoform TrkA-III; TrkA-III; NTRK1 Isoform TrkA-III; EC 2.7.10.1; Neurotrophic Tyrosine Kinase Receptor Type 1 Isoform TrkA-III; Tropomyosin-Related Kinase A Isoform TrkA-III;

NCIt definition : High affinity nerve growth factor receptor isoform TrkA-III (698 aa, 77 kDa) is encoded by the human NTRK1 gene. This protein is involved in constitutive signaling and tyrosine phosphorylation.;

NCIt note : High affinity nerve growth factor receptor isoform TrkA-III does not bind NGF and does not interact with the adaptor molecules GRB2 and FRS2. (UniProt); High Affinity Nerve Growth Factor Receptor Isoform TrkA-III isoform is specifically expressed by pluripotent neural stem and neural crest progenitors and its expression is stimulated by hypoxia. (UniProt);

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02/06/2025


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