CD2 Antigen Cytoplasmic Tail-Binding Protein 2

Preferred Label : CD2 Antigen Cytoplasmic Tail-Binding Protein 2;

NCIt synonyms : CD2 Tail-Binding Protein 2; CD2 Antigen-Binding Protein 2; CD2 Cytoplasmic Domain-Binding Protein 2; U5-52K; U5 SnRNP 52K Protein; CD2BP2;

NCIt definition : CD2 antigen cytoplasmic tail-binding protein 2 (341 aa, 38 kDa) is encoded by the human CD2BP2 gene. This protein plays a role in mRNA splicing and T-cell activation.;

NCIt note : In the cytoplasm, CD2 antigen cytoplasmic tail-binding protein 2 binds to the cytoplasmic tail of T-cell surface antigen CD2 and regulates T-cell activation. In the nucleus, CD2 antigen cytoplasmic tail-binding protein 2 is part of the component of the U5 snRNP complex, which regulates RNA splicing.;

Details

Origin ID

C126502;

UMLS CUI

C1438413;

Automatic exact mappings (from CISMeF team)
- Cd2 antigen-binding protein 2 [OMIM gene]
OMIM relation
- Cd2 antigen-binding protein 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CD2BP2 protein, human [MeSH Supplementary Concept]
- CD2BP2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CD2BP2 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- RNA Splicing [NCIt concept]
- T-Cell Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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