Oncostatin-M-Specific Receptor Subunit Beta

Preferred Label : Oncostatin-M-Specific Receptor Subunit Beta;

NCIt synonyms : Oncostatin M Receptor; OSMR; Oncostatin-M Specific Receptor Beta Subunit; OSMRB; IL-31RB; IL-31R-Beta; Oncostatin-M Specific Receptor Subunit Beta; IL-31 Receptor Subunit Beta; IL-31R Subunit Beta; Interleukin-31 Receptor Subunit Beta;

NCIt definition : Oncostatin-M-specific receptor subunit beta (979 aa, 111 kDa) is encoded by the human OSMR gene. This protein plays a role in interleukin-31 and oncostatin-M binding and ligand-dependent signal transduction.;

NCIt note : Oncostatin-M-specific receptor subunit beta is found in either a heterodimeric complex with IL6ST to form the type II oncostatin M receptor or a heterodimeric complex with IL31RA to form the interleukin-31 receptor. (UniProt);

Details

Origin ID

C34019;

UMLS CUI

C1721395;

Automatic exact mappings (from CISMeF team)
- interleukin 6 cytokine family signal transducer [HGNC gene]
OMIM relation
- Oncostatin M receptor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- OSMR protein, human [MeSH concept]
- OSMR protein, human [MeSH Supplementary Concept]
Validated automatic mappings to NTBT
- receptors, oncostatin M [MeSH concept]
- receptors, oncostatin m [MeSH Descriptor]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- OSMR Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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