Insulin-Like Growth Factor-Binding Protein 4

Preferred Label : Insulin-Like Growth Factor-Binding Protein 4;

NCIt synonyms : IGFBP4; IGFBP-4; IGF Binding Protein 4; IGF-Binding Protein 4; Insulin-Like Growth Factor Binding Protein 4; IBP-4; Insulin-Like Growth Factor-Binding Protein-4;

NCIt definition : Insulin-like growth factor-binding protein 4 (258 aa, 28 kDa) is encoded by the human IGFBP4 gene. This protein plays a role in both insulin-like growth factor binding and downstream signal transduction.;

Details

Origin ID

C17507;

UMLS CUI

C4082567;

Currated CISMeF NLP mapping
- Insulin-Like growth factor binding protein 4 [MeSH Descriptor]
- Insulin-Like growth factor binding protein 4 [MeSH concept]
False automatic mappings
- Insulin-like growth factor binding protein 4 (substance) [SNOMED CT concept]
OMIM relation
- Insulin-like growth factor-binding protein 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- IGFBP4 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- IGFBP4 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_is_biomarker_type
- Risk Marker [NCIt concept]
gene_product_is_element_in_pathway
- Food Intake and Energy Homeostasis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Inhibition of Cell Proliferation [NCIt concept]
- Intracellular Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Signal Transduction [NCIt concept]
- Skeletal Development [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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