Mineralocorticoid Receptor

Preferred Label : Mineralocorticoid Receptor;

NCIt synonyms : NR3C2; MCR; MLR; Nuclear Receptor Subfamily 3 Group C Member 2; MR; Aldosterone Receptor; Receptors, Mineralocorticoid;

NCIt definition : Mineralocorticoid receptor (984 aa, 107 kDa) is encoded by the human NR3C2 gene. This protein is involved in the modulation of mineralcorticoid and glucocorticoid-dependent gene transcription.;

Details

Origin ID

C17312;

UMLS CUI

C3254418;

Currated CISMeF NLP mapping
- Aldosterone receptors [LOINC component]
- receptors, aldosterone [MeSH concept]
- receptors, mineralocorticoid [MeSH Descriptor]
- receptors, mineralocorticoid [MeSH concept]
OMIM relation
- Nuclear receptor subfamily 3, group C, member 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- NR3C2 protein, human [MeSH concept]
- NR3C2 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- NR3C2 Gene [NCIt concept]
- Nuclear Receptor Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Hormone Receptor [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Nuclear Hormone Receptor Superfamily [NCIt concept]
gene_product_has_structural_domain_or_motif
- Hormone Receptor DNA-Binding Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Aldosterone-Regulated Sodium Reabsorption Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- DNA Binding [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Maturation [NCIt concept]
- Pattern Formation [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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