Selective Serotonin Reuptake Inhibitor

Preferred Label : Selective Serotonin Reuptake Inhibitor;

NCIt related terms : SSRI;

NCIt definition : Any agent that increases the extracellular level of the neurotransmitter serotonin (5-HT) by inhibiting its reuptake into the presynaptic cell. Increased level in the synaptic cleft prolongs the action of 5-HT on the postsynaptic receptor. This type of agent is typically used as an antidepressant and in the treatment of anxiety disorders and some personality disorders. They are also typically effective and used in treating some cases of insomnia.;

Alternative definition : NCI-GLOSS: A type of drug that is used to treat depression. Selective serotonin reuptake inhibitors slow the process by which serotonin (a substance that nerves use to send messages to one another) is reused by nerve cells that make it. This increases the amount of serotonin available for stimulating other nerves.;

ChEBI ID : CHEBI:50949;

Codes from synonyms : CDR0000335507; CDR0000335509;

Details

Origin ID

C94725;

UMLS CUI

C0360105;

Automatic exact mappings (from CISMeF team)
- Selective Serotonin Reuptake Inhibitors [MeSH Descriptor]
- Selective serotonin reuptake inhibitors [ICHI section]
- Serotonin reuptake inhibitor (disposition) [SNOMED CT concept]
- antidepressants [MedlinePlus Topic]
- magnetic resonance imaging [MeSH Descriptor]
CISMeF manual mappings
- Antidepressant selective serotonin reuptake inhibitor [ICD-11 Extension code]
Currated CISMeF NLP mapping
- Selective Serotonin Reuptake Inhibitors [MeSH concept]
- Selective serotonin reuptake inhibitors [Bloc CIM-11]
- Substance with serotonin re-uptake inhibitor mechanism of action (substance) [SNOMED CT concept]
- selective serotonin reuptake inhibitors [ATC Code]
See also inter- (CISMeF)
- Product containing selective serotonin re-uptake inhibitor (product) [SNOMED CT concept]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Antidepressant selective serotonin reuptake inhibitor [ICD-11 Extension code]
- Product containing selective serotonin re-uptake inhibitor (product) [SNOMED CT concept]
- Selective Serotonin Reuptake Inhibitors [MeSH concept]
- Selective Serotonin Reuptake Inhibitors [MeSH Descriptor]
- Selective serotonin reuptake inhibitors [Bloc CIM-11]
- Substance with serotonin re-uptake inhibitor mechanism of action (substance) [SNOMED CT concept]
- selective serotonin reuptake inhibitors [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

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