Coagulation Factor V

Preferred Label : Coagulation Factor V;

NCIt synonyms : Activated Protein C Cofactor; Proaccelerin, Labile Factor; Labile Factor; F5; Factor V;

NCIt definition : Coagulation factor V (2224 aa, 252 kDa) is encoded by the human F5 gene. This protein plays a role in the coagulation cascade.;

NCIt note : Coagulation factor V has no activity until it is cleaved by thrombin into two chains, called coagulation factor V heavy chain and coagulation factor V light chain. The two chains are non-covalently bound in a complex, factor Va, which is a cofactor that enhances the enzymatic activity of coagulation factor Xa.;

Détails

Origin ID

C91335;

UMLS CUI

C1448834;

Automatic exact mappings (from CISMeF team)
- Coagulation factor IX (substance) [SNOMED CT concept]
- Coagulation factor V [OMIM gene]
- Coagulation factor ix [OMIM gene]
- Patched 1 [OMIM gene]
- Taste receptor, type 2, member 38 [OMIM gene]
- Thyroid cancer, nonmedullary, 1 [OMIM Phenotype]
- coagulation factor V [ORDO Gene]
- coagulation factor V [HGNC gene]
- coagulation factor v [medical devices type]
- coiled-coil domain containing 6 [ORDO Gene]
- factor IX [MeSH Descriptor]
- factor IX [Blood Transfusion thesaurus concept]
- ret proto-oncogene [ORDO Gene]
OMIM relation
- Coagulation factor V [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- fv protein, human [MeSH Supplementary Concept]
- fv protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Coagulation Factor Gene [NCIt concept]
- F5 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma [NCIt concept]
gene_product_has_gene_product_variant
- F5 NP_000121.2:p.R534Q [NCIt concept]
- F5 Protein Variant [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Complement and Coagulation Cascade [NCIt concept]
- Extrinsic Prothrombin Activation Pathway [NCIt concept]
- Intrinsic Prothrombin Activation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Coagulation Process [NCIt concept]
- Ligand Binding [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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