Dynactin Subunit 1

Preferred Label : Dynactin Subunit 1;

NCIt synonyms : DAP-150; 150 kDa Dynein-Associated Polypeptide; p150-glued; p135; DP-150;

NCIt definition : Dynactin subunit 1 (1278 aa, 142 kDa) is encoded by the human DCTN1 gene. This protein is involved in the dynein-mediated retrograde transport of vesicles and organelles along microtubules.;

Details

Origin ID

C122877;

UMLS CUI

C4049829;

Automatic exact mappings (from CISMeF team)
- Dynactin Complex [MeSH Descriptor]
- dynactin subunit 1 [MeSH concept]
- dynactin subunit 1 [ORDO Gene]
- dynactin subunit 1 [HGNC gene]
OMIM relation
- Dynactin 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- DCTN1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DCTN1 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Cytoskeleton [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Huntington's Disease Pathway [NCIt concept]
- N-Cadherin Signaling Pathway [NCIt concept]
- Vasopressin-Regulated Water Reabsorption Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Intracellular Transport [NCIt concept]
- Ligand Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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