Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A

Preferred Label : Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A;

NCIt synonyms : FcR-10; FcRIIIA; CD16; FCGR3; Fc-Gamma RIIIA; Fc-Gamma RIII-Alpha; Low Affinity IgG Fc Receptor IIIA; FcgammaRIIIA; IGFR3; Fc-Gamma RIII; FCG3; IgG Fc Receptor III-2; FCGR3A; CD16A; FcRIII; FCRIII-2; Fc Gamma Receptor III-A; CD16A Antigen; Immunoglobulin G Fc Receptor III-2; IgG Fc Receptor IIIA; IgG-Fc-Receptor-IIIA;

NCIt definition : Low affinity immunoglobulin gamma Fc region receptor III-A (254 aa, 29 kDa) is encoded by the human FCGR3A gene. This protein is involved in antibody-mediated immunity.;

NCIt note : FCGR3B exists in a hetero-oligomeric complex with the Fc epsilon receptor I gamma subunit and/or the CD3 zeta subunit. It can also act as a soluble receptor produced by proteolytic cleavage.;

Details

Origin ID

C38559;

UMLS CUI

C1521898;

OMIM relation
- Fc fragment of igg receptor iiia [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- FCGR3A protein, human [MeSH concept]
- FCGR3A protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- FCGR3A Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Fc-Gamma Receptor III [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Systemic Lupus Erythematosus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Antibody-Dependent Cellular Cytotoxicity [NCIt concept]
- Immune Response Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Phagocytosis [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
is_target
- Acimtamig [NCIt concept]
- Anti-EGFR/CD16A Bispecific Antibody AFM24 [NCIt concept]

Keyword's position in hierarchy(ies) :

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