Sialic Acid-Binding Ig-Like Lectin 15

Preferred Label : Sialic Acid-Binding Ig-Like Lectin 15;

NCIt synonyms : CD33 Molecule-Like 3; Sialic Acid-Binding Immunoglobulin-Like Lectin 15; Sialic Acid Binding Ig Like Lectin 15; S15; Siglec-15; SIGLEC15; Sialic Acid Binding Ig-Like Lectin 15; CD33 Antigen-Like 3;

NCIt definition : Sialic acid-binding Ig-like lectin 15 (328 aa, 36 kDa) is encoded by the human SIGLEC15 gene. This protein plays a role in both sialylated glycan binding and innate immunity.;

NCI Metathesaurus CUI : CL937924;

Details

Origin ID

C158386;

UMLS CUI

C4761542;

Automatic exact mappings (from CISMeF team)
- Sialic acid-binding immunoglobulin-like lectin 15 [OMIM gene]
- ribosomal protein S15 [ORDO Gene]
- sialic acid binding Ig like lectin 15 [HGNC gene]
OMIM relation
- Sialic acid-binding immunoglobulin-like lectin 15 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- SIGLEC15 Gene [NCIt concept]
gene_product_expressed_in_tissue
- Lymph Node [NCIt concept]
- Spleen [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
gene_product_has_biochemical_function
- Lectin [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
- Immunoglobulin Family Protein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Immunoglobulin-Like V-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Immunity [NCIt concept]
- Ligand Binding [NCIt concept]
is_target
- Anti-S15 Monoclonal Antibody NC318 [NCIt concept]
- Anti-Siglec-15 Monoclonal Antibody PYX-106 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients