Monocarboxylate Transporter 3

Preferred Label : Monocarboxylate Transporter 3;

NCIt synonyms : MCT 3; Solute Carrier Family 16 Member 8; SLC16A8;

NCIt definition : Monocarboxylate transporter 3 (504 aa, 52 kDa) is encoded by the human SLC16A8 gene. This protein plays a role in transmembrane transport of monocarboxylates.;

NCIt note : Monocarboxylate transporter 3 may transport lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. (UniProt);

NCI Metathesaurus CUI : CL522178;

Details

Origin ID

C134627;

UMLS CUI

C4521277;

Automatic exact mappings (from CISMeF team)
- Solute carrier family 16 (monocarboxylic acid transporter), member 8 [OMIM gene]
- solute carrier family 16 member 8 [HGNC gene]
OMIM relation
- Solute carrier family 16 (monocarboxylic acid transporter), member 8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- SLC16A8 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Retinal Pigment Epithelium [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Solute Carrier Family [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Intermediary Metabolic Process [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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