NCIt synonyms : Antigen Identified By Monoclonal Antibody TRA-2-10; Measles Virus Receptor; CD46 Antigen; Complement Membrane Cofactor Protein; Antigen Defined By Monoclonal Antibody TRA-2-10; Trophoblast Leucocyte Common Antigen; Trophoblast-Lymphocyte Cross-Reactive Antigen; TLX; Trophoblast Leukocyte Common Antigen;
NCIt definition : Membrane cofactor protein (392 aa, 44 kDa) is encoded by the human CD46 gene. This
protein is involved in the classical complementation pathway, pathogen binding, fertilization
and T-cell differentiation.;
NCIt note : Membrane cofactor protein is a receptor for adenovirus subgroup B2 and Ad3, cultured
measles virus and herpesvirus 6, and may also bind the pathogenic bacteria Neisseria
and Streptococcus pyogenes. (UniProt);