Membrane Cofactor Protein

Preferred Label : Membrane Cofactor Protein;

MeSH definition : A ubiquitously expressed complement receptor that binds COMPLEMENT C3B and COMPLEMENT C4B and serves as a cofactor for their inactivation. CD46 also interacts with a wide variety of pathogens and mediates immune response.; A ubiquitously expressed complement receptor that binds COMPLEMENT C3B and COMPLEMENT C4B and serves as a co-factor for their inactivation by COMPLEMENT FACTOR I. It also interacts with a wide variety of pathogens and mediates the immune response.;

MeSH synonym : trophoblast leukocyte common antigen; cd46 antigens; trophoblast-leukocyte common antigen; common antigen, trophoblast-leukocyte; cd46 antigen; antigen, cd46; Antigens, CD46;

Is substance : O;

Details

Origin ID

D051916;

UMLS CUI

C0285488;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Currated CISMeF NLP mapping
- CD46 [LOINC component]
- Lymphocyte antigen CD46 (substance) [SNOMED CT concept]
- lymphocyte antigen cd46 [SNOMED Notion]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- Membrane Cofactor Protein [MeSH concept]
Related MeSH Supplementary Concept(s)
- CD46 protein, human [MeSH Supplementary Concept]
- Cd46 protein, rat [MeSH Supplementary Concept]
- mcp protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- CD46 [LOINC component]
- Lymphocyte antigen CD46 (substance) [SNOMED CT concept]
- lymphocyte antigen cd46 [SNOMED Notion]
- membrane cofactor protein [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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