Negative Regulation of Complement Activation

Preferred Label : Negative Regulation of Complement Activation;

NCIt synonyms : Complement Suppression;

NCIt definition : Any physiologic process in which the C3 and C5 convertases are disassembled or proteolytically inactivated, limiting the persistence of convertase activity. This process is involved in regulating the extent of action of the complement system.;

Details

Origin ID

C40595;

UMLS CUI

C1516746;

Currated CISMeF NLP mapping
- negative regulation of complement activation [GO term]
Semantic type(s)
- Cell Function [UMLS semantic type]
UMLS correspondences (same concept)
- negative regulation of complement activation [GO term]
biological_process_has_initiator_chemical_or_drug
- Antigen [NCIt concept]
biological_process_involves_gene_product
- CD59 Glycoprotein [NCIt concept]
- Complement Decay-Accelerating Factor [NCIt concept]
- Complement Factor I [NCIt concept]
- Membrane Cofactor Protein [NCIt concept]
- V-Set and Immunoglobulin Domain-Containing Protein 4 [NCIt concept]
biological_process_is_part_of_process
- Host Defense Mechanism [NCIt concept]
- Immunity [NCIt concept]
process_involves_gene
- CD46 Gene [NCIt concept]
- CD46 wt Allele [NCIt concept]
- CD55 Gene [NCIt concept]
- CD55 wt Allele [NCIt concept]
- CD59 Gene [NCIt concept]
- CD59 wt Allele [NCIt concept]
- CFI Gene [NCIt concept]
- CFI wt Allele [NCIt concept]
- SERPING1 Gene [NCIt concept]
- SERPING1 wt Allele [NCIt concept]
- VSIG4 Gene [NCIt concept]
- VSIG4 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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