Complement Decay-Accelerating Factor

Preferred Label : Complement Decay-Accelerating Factor;

NCIt synonyms : CD55 Antigen; CD55; Decay Accelerating Factor; DAF; CD Antigen CD55; Decay-Accelerating Factor; CD55 Protein; Decay-Accelerating Factor for Complement;

NCIt definition : Complement decay-accelerating factor (381 aa, 41 kDa) is encoded by the human CD55 gene. This protein plays a role in the negative regulation of the complement cascade.;

NCIt note : Complement decay-accelerating factor prevents the assembly of C3-convertase or accelerates the disassembly of preformed convertase, thus blocking the compelment cascade.; Antigens present on complement decay-accelerating factor are responsible for the Cromer blood group system.;

Details

Origin ID

C95931;

UMLS CUI

C4721410;

Automatic exact mappings (from CISMeF team)
- CD55 [LOINC component]
- CD55 cells [LOINC component]
- CD55 molecule (Cromer blood group) [ORDO Gene]
- Cd55 antigen [OMIM gene]
- daf [EDAM format]
- decay accelerating factor [SNOMED Notion]
- persons with hearing impairments [MeSH Descriptor]
Currated CISMeF NLP mapping
- CD55 Antigens [MeSH Descriptor]
- CD55 Antigens [MeSH concept]
- Complement decay accelerating factor [LOINC component]
- Decay accelerating factor (substance) [SNOMED CT concept]
OMIM relation
- Cd55 antigen [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- CD55 Antigens [MeSH Descriptor]
- CD55 Antigens [MeSH concept]
- Complement decay accelerating factor [LOINC component]
- Decay accelerating factor (substance) [SNOMED CT concept]
- decay accelerating factor [SNOMED Notion]
- lymphocyte antigen cd55 [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CD55 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Sushi Domain [NCIt concept]
gene_product_is_element_in_pathway
- Complement and Coagulation Cascade [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- Viral Myocarditis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Negative Regulation of Complement Activation [NCIt concept]
is_target
- Gebasaxturev [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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