Gebasaxturev - CISMeF

Preferred Label : Gebasaxturev;

NCIt synonyms : CVA21; Coxsackievirus A21; Coxsackievirus V937;

NCIt definition : A preparation of naturally occurring, oncolytic enterovirus, with potential antineoplastic activity. Upon administration, gebasaxturev targets and binds to intracellular adhesion molecule 1 (ICAM-1) and decay acceleration factor (DAF), both cell surface molecules that are overexpressed on certain malignant cells. After entering the cells, gebasaxturev replicates in these cancer cells, thereby causing cancer cell lysis. This results in a reduction of tumor cell growth.;

UNII : 4B57CWT710;

CAS number : 1802360-06-0;

Drug name : CAVATAK;

Molecule name : V-937; V 937;

Details

Origin ID

C61493;

UMLS CUI

C1440507;

Currated CISMeF NLP mapping
- Coxsackievirus A21 [LOINC component]
Semantic type(s)
- Virus [UMLS semantic type]
UMLS correspondences (same concept)
- Coxsackievirus A21 [LOINC component]
- Human coxsackievirus A21 (organism) [SNOMED CT concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Complement Decay-Accelerating Factor [NCIt concept]
- Intercellular Adhesion Molecule 1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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