Intercellular Adhesion Molecule 1

Preferred Label : Intercellular Adhesion Molecule 1;

NCIt synonyms : ICAM1; CD54; ICAM-1; Intercellular Adhesion Molecule-1; Major Group Rhinovirus Receptor; CD54 Antigen; Human Rhinovirus Receptor;

NCIt definition : Intercellular adhesion molecule 1 (532 aa, 58 kDa) is encoded by the human ICAM1 gene. This protein plays a role in integrin binding, immune signaling and leukocyte transendothelial migration.;

NCIt note : Intercellular adhesion molecule 1 is a ligand for LFA antigens and is the major human rhinovirus receptor.;

Details

Origin ID

C17304;

UMLS CUI

C3493229;

Currated CISMeF NLP mapping
- intercellular adhesion Molecule-1 [MeSH Descriptor]
- intercellular adhesion Molecule-1 [MeSH concept]
OMIM relation
- Intercellular adhesion molecule 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- ICAM1 protein, human [MeSH concept]
- ICAM1 protein, human [MeSH Supplementary Concept]
- Lymphocyte antigen CD54 (substance) [SNOMED CT concept]
- intercellular adhesion Molecule-1 [MeSH concept]
- intercellular adhesion Molecule-1 [MeSH Descriptor]
- lymphocyte antigen cd54 [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Adhesion Molecule Gene [NCIt concept]
- ICAM1 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- B-Lymphocyte [NCIt concept]
- Monocyte [NCIt concept]
- T-Lymphocyte [NCIt concept]
gene_product_has_associated_anatomy
- Endothelial Cell [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Glycoprotein [NCIt concept]
- Immunoglobulin Family Protein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- AlphaM/Beta2 Integrin Signaling Pathway [NCIt concept]
- CTL-mediated Immune Response Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Glucocorticoid Receptor Regulatory Network [NCIt concept]
- Granulocyte Adhesion Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- Local Acute Inflammatory Response Pathway [NCIt concept]
- Lymphocyte Adhesion Pathway [NCIt concept]
- Malaria Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Thromboxane A2 Receptor Family Signaling Pathway [NCIt concept]
- Viral Myocarditis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
is_target
- Autologous Anti-ICAM-1-CAR-CD28-4-1BB-CD3zeta-expressing T-cells AIC100 [NCIt concept]
- Bersanlimab [NCIt concept]
- Gallium Ga 68-ICAM-1pep [NCIt concept]
- Gebasaxturev [NCIt concept]

Keyword's position in hierarchy(ies) :

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