Preferred Label : Gallium Ga 68-ICAM-1pep;
NCIt synonyms : Gallium Ga 68-CD54pep; 68Ga-ICAM-1pep; 68Ga-CD54pep;
NCIt definition : A radioconjugate composed of ICAM-1pep, an intercellular adhesion molecule-1 (ICAM-1;
CD54)-targeted tracer, labeled with the radioisotope gallium Ga 68, with potential
use as a tracer for ICAM-1 during positron emission tomography/computed tomography
(PET/CT). Upon administration of gallium Ga 68-ICAM-1pep, the ICAM-1pep moiety targets
and binds to ICAM-1. Upon binding, ICAM-1pep expression can be detected during PET/CT
imaging. ICAM-1, an inducible glycoprotein of the immunoglobulin superfamily (IgSF)
normally expressed on leukocytes and endothelial cells, may be overexpressed in a
variety of cancers. Its expression may also be up-regulated in nonirradiated tumors
that are responsive to radiation therapy.;
NCI Metathesaurus CUI : CL1648070;
Origin ID : C178581;
UMLS CUI : C5555143;
Semantic type(s)
- concept_is_in_subset
- has_target
