Host Defense Mechanism

Preferred Label : Host Defense Mechanism;

NCIt synonyms : Host Defense;

NCIt definition : Host Defenses against pathology include physical barriers to pathogens, immediate nonspecific and constitutive (innate) defenses, specific inducible immune responses, metabolic and physiologic homeostatic mechanisms, detoxification, repair processes, and healing mechanisms.;

Details

Origin ID

C18839;

UMLS CUI

C0520990;

Currated CISMeF NLP mapping
- Host defense, function (observable entity) [SNOMED CT concept]
- host defense [SNOMED Notion]
Semantic type(s)
- Organ or Tissue Function [UMLS semantic type]
UMLS correspondences (same concept)
- Host defense, function (observable entity) [SNOMED CT concept]
- host defense [SNOMED Notion]
biological_process_involves_gene_product
- Beclin-1 [NCIt concept]
- Beta-Defensin 103 [NCIt concept]
- C3a Anaphylatoxin [NCIt concept]
- CD160 Antigen [NCIt concept]
- Complement C3 [NCIt concept]
- Complement C3 Beta Chain [NCIt concept]
- Complement C3d [NCIt concept]
- Complement Factor D [NCIt concept]
- Dual Oxidase 1 [NCIt concept]
- Dual Oxidase 2 [NCIt concept]
- Endoribonuclease ZC3H12A [NCIt concept]
- Fibronectin [NCIt concept]
- Galectin-3-Binding Protein [NCIt concept]
- Interleukin-12 Receptor Subunit Beta-1 [NCIt concept]
- Interleukin-12 Receptor Subunit Beta-2 [NCIt concept]
- Myeloperoxidase [NCIt concept]
- Protegrin [NCIt concept]
- Transmembrane Protease Serine 11D [NCIt concept]
- Tyrosine-Protein Kinase ITK/TSK [NCIt concept]
- Tyrosine-Protein Kinase TXK [NCIt concept]
process_includes_biological_process
- Activation of Membrane Attack Complex [NCIt concept]
- B-Cell Differentiation [NCIt concept]
- Calcium Homeostasis [NCIt concept]
- Carcinogen Metabolism [NCIt concept]
- Cell-Mediated Immunity [NCIt concept]
- Cholesterol Homeostasis [NCIt concept]
- Complement Activation [NCIt concept]
- Complement-Dependent Cytotoxicity [NCIt concept]
- Detoxification [NCIt concept]
- Drug Metabolism [NCIt concept]
- Drug Metabolism Induction [NCIt concept]
- Drug Metabolism Inhibition [NCIt concept]
- Ethanol Metabolism [NCIt concept]
- Heat-Shock Response [NCIt concept]
- Herd Immunity [NCIt concept]
- Homeostatic Process [NCIt concept]
- Humoral Immunity [NCIt concept]
- Immunity [NCIt concept]
- Immunopotentiation [NCIt concept]
- Immunoregulation [NCIt concept]
- Immunosuppressive Effect [NCIt concept]
- Inflammatory Response [NCIt concept]
- Leukocyte Trafficking [NCIt concept]
- Leukocyte Trafficking Induction [NCIt concept]
- Leukocyte Trafficking Inhibition [NCIt concept]
- Megakaryocyte Proliferation [NCIt concept]
- Mucosal Immunity [NCIt concept]
- Negative Regulation of Complement Activation [NCIt concept]
- Negative Regulation of Inflammatory Response Process [NCIt concept]
- Neuronophagia [NCIt concept]
- Nitrosamine Metabolism [NCIt concept]
- Phagocytosis [NCIt concept]
- Phase I Detoxification [NCIt concept]
- Phase II Detoxification [NCIt concept]
- Quinone Metabolism [NCIt concept]
- Suppression of Cancer Cell Invasion [NCIt concept]
- T-Cell Differentiation [NCIt concept]
- T-Cell Differentiation in the Thymus [NCIt concept]
- Thymic T-Cell Selection [NCIt concept]
- Tolerance Induction in Solid Organ Transplantation [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]
- pH Homeostasis [NCIt concept]
process_involves_gene
- BECN1 Gene [NCIt concept]
- BECN1 wt Allele [NCIt concept]
- C3 Gene [NCIt concept]
- C3 wt Allele [NCIt concept]
- CD160 Gene [NCIt concept]
- CD160 wt Allele [NCIt concept]
- DEFB103A Gene [NCIt concept]
- DEFB103A wt Allele [NCIt concept]
- DEFB103B Gene [NCIt concept]
- DEFB103B wt Allele [NCIt concept]
- DUOX1 Gene [NCIt concept]
- DUOX1 wt Allele [NCIt concept]
- DUOX2 Gene [NCIt concept]
- DUOX2 wt Allele [NCIt concept]
- FN1 Gene [NCIt concept]
- FN1 wt Allele [NCIt concept]
- IL12RB1 Gene [NCIt concept]
- IL12RB1 wt Allele [NCIt concept]
- IL12RB2 Gene [NCIt concept]
- IL12RB2 wt Allele [NCIt concept]
- ITK Gene [NCIt concept]
- ITK wt Allele [NCIt concept]
- LGALS3BP Gene [NCIt concept]
- LGALS3BP wt Allele [NCIt concept]
- MPO Gene [NCIt concept]
- MPO wt Allele [NCIt concept]
- TMPRSS11D Gene [NCIt concept]
- TMPRSS11D wt Allele [NCIt concept]
- TXK Gene [NCIt concept]
- TXK wt Allele [NCIt concept]
- ZC3H12A Gene [NCIt concept]
- ZC3H12A wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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