" /> Myeloperoxidase - CISMeF





Preferred Label : Myeloperoxidase;

NCIt synonyms : EC 1.11.1.7; MPO;

NCIt definition : Myeloperoxidase (745 aa, 84 kDa) is encoded by the human MPO gene. This protein is involved in the regulation of the innate host defense through the production of hypohalous acids.;

Alternative definition : CDISC: An antigen encoded by the MPO gene that regulates innate immunity through hypohalous acids production. It can be considered as an autoantigen and is commonly associated with autoimmune systemic vasculitis diseases, cystic fibrosis, COPD and other inflammatory conditions.;

NCIt note : Myeloperoxidase is synthesized as a single chain precursor that is cleaved into a light and heavy chain. The mature enzyme is a tetramer composed of 2 light chains and 2 heavy chains. (EntrezGene);

UNII : JQZ6YM58U5;

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29/04/2024


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