Dual Oxidase 1

Preferred Label : Dual Oxidase 1;

NCIt synonyms : DUOX1; Thyroid Oxidase 1; EC 1.6.3.1; EC 1.11.1.-; Large NOX 1; Long NOX 1; NADPH Thyroid Oxidase 1;

NCIt definition : Dual oxidase 1 (1551 aa, 177 kDa) is encoded by the human DUOX1 gene. This protein is involved in the positive regulation of both lactoperoxidase antimicrobial activity and thyroid hormone biosynthesis.;

Details

Origin ID

C200905;

UMLS CUI

C1448042;

OMIM relation
- Dual oxidase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- DUOX1 protein, human [MeSH Supplementary Concept]
- DUOX1 protein, human [MeSH concept]
gene_encodes_gene_product
- DUOX1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Calcium Binding Protein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- EF-Hand Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Biosynthetic Process [NCIt concept]
- Calcium Binding [NCIt concept]
- Host Defense Mechanism [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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