Tyrosine-Protein Kinase ITK/TSK

Preferred Label : Tyrosine-Protein Kinase ITK/TSK;

NCIt synonyms : T-Cell ITK/TSK Homolog; EMT; Kinase EMT; Tyrosine-Protein Kinase LYK; PSCTK2; T-Cell-Specific Kinase; LYK; Interleukin-2-Inducible T-Cell Kinase; IL2-Inducible T-Cell Kinase; ITK; EC 2.7.10.2;

NCIt definition : Tyrosine-protein kinase ITK/TSK (620 aa, 75 kDa) is encoded by the human ITK gene. This protein is involved in tyrosine phosphorylation and immunity.;

Details

Origin ID

C29753;

UMLS CUI

C1567665;

Currated CISMeF NLP mapping
- ITK protein, human [MeSH concept]
OMIM relation
- Il2-inducible t-cell kinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ITK protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- ITK Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- Tyrosine Kinase Domain [NCIt concept]
gene_product_is_element_in_pathway
- Chemokine Signaling Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Activation Co-Stimulatory Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Host Defense Mechanism [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]
is_target
- Soquelitinib [NCIt concept]

Keyword's position in hierarchy(ies) :

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