ITK wt Allele - CISMeF

Preferred Label : ITK wt Allele;

NCIt synonyms : IL2-Inducible T-Cell Kinase wt Allele; PSCTK2; LYK; EMT;

NCIt definition : Human ITK wild-type allele is located within 5q31-q32 and is approximately 74 kb in length. This allele, which encodes tyrosine-protein kinase ITK/TSK protein, plays a role in signal transduction.;

NCIt note : ITK gene expression is induced by interleukin-2 in T-cells and natural killer cells.;

GenBank Accession Number : NM_005546;

Details

Origin ID

C51081;

UMLS CUI

C1706224;

OMIM relation
- Il2-inducible t-cell kinase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 5: 156540485-156614687 [NCIt concept]
gene_in_chromosomal_location
- 5q31-q32 [NCIt concept]
gene_is_element_in_pathway
- Chemokine Signaling Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T-Cell Activation Co-Stimulatory Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Host Defense Mechanism [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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