Transmembrane Protease Serine 11D

Preferred Label : Transmembrane Protease Serine 11D;

NCIt synonyms : Transmembrane Serine Protease 11D; EC 3.4.21.-; Airway Trypsin-Like Protease; Adrenal Secretory Serine Protease; Airway Trypsin Like Protease; TMPRSS11D;

NCIt definition : Transmembrane protease serine 11D (418 aa, 46 kDa) is encoded by the human TMPRSS11D gene. This protein may play a role in host defense processes in the lungs, proteolytic processing of angiotensin-converting enzyme 2 and in the entry of coronaviruses into host cells through proteolytically processing of spike proteins.;

NCI Metathesaurus CUI : CL1399679;

Details

Origin ID

C189970;

UMLS CUI

C5226424;

Automatic exact mappings (from CISMeF team)
- Transmembrane protease, serine 11d [OMIM gene]
- transmembrane serine protease 11D [HGNC gene]
OMIM relation
- Transmembrane protease, serine 11d [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- TMPRSS11D protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
- TMPRSS11D Gene [NCIt concept]
gene_product_expressed_in_tissue
- Bronchus Submucosa [NCIt concept]
- Trachea Submucosa [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Host Defense Mechanism [NCIt concept]
- Hydrolysis [NCIt concept]
- Proteolysis [NCIt concept]
- Proteolytic Processing [NCIt concept]
- Virus-Induced Membrane Fusion [NCIt concept]

Keyword's position in hierarchy(ies) :

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