Importin Subunit Alpha-1

Preferred Label : Importin Subunit Alpha-1;

NCIt synonyms : Importin Alpha-1; RAG Cohort Protein 1; SRP1-Alpha; KPNA2; Karyopherin Subunit Alpha-2;

NCIt definition : Importin subunit alpha-1 (529 aa, 58 kDa) is encoded by the human KPNA2 gene. This protein plays a role in the import of proteins into the nucleus.;

Details

Origin ID

C179698;

UMLS CUI

C1448914;

OMIM relation
- Karyopherin alpha-2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- KPNA2 protein, human [MeSH Supplementary Concept]
- KPNA2 protein, human [MeSH concept]
concept_is_in_subset
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- KPNA2 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Cytoplasm [NCIt concept]
- Nuclear Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- Armadillo Repeat [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Nuclear Localization Signal [NCIt concept]
gene_product_is_element_in_pathway
- Calcineurin-Dependent NFAT Signaling Pathway in Lymphocytes [NCIt concept]
- Protein Import into Nucleus Pathway [NCIt concept]
- Regulation of Cytoplasmic and Nuclear SMAD2/3 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Nucleocytoplasmic Transport [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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