Inositol 1,4,5-Trisphosphate Receptor Type 1

Preferred Label : Inositol 1,4,5-Trisphosphate Receptor Type 1;

NCIt synonyms : Type 1 InsP3 Receptor; IP3 Receptor Isoform 1; IP3R1; IP3R; InsP3R1; Type 1 Inositol 1,4,5-Trisphosphate Receptor; Inositol-1-4-5-Triphosphate Receptor Type-1; Inositol 1,4,5-Triphosphate Receptor Type 1; IP3R 1;

NCIt definition : Inositol 1,4,5-trisphosphate receptor type 1 (2758 aa, 314 kDa) is encoded by the human ITPR1 gene. This protein is involved in intracellular calcium transport.;

Details

Origin ID

C29754;

UMLS CUI

C0626645;

Currated CISMeF NLP mapping
- inositol 1,4,5-trisphosphate receptor type 1 [MeSH concept]
OMIM relation
- Inositol 1,4,5-triphosphate receptor, type 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- ITPR1 protein, human [MeSH concept]
- ITPR1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- ITPR1 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alzheimer's Disease Pathway KEGG [NCIt concept]
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Gap Junction Assembly Pathway [NCIt concept]
- Gastric Acid Secretion Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- Huntington's Disease Pathway [NCIt concept]
- Long-Term Depression Pathway [NCIt concept]
- Long-Term Potentiation Pathway [NCIt concept]
- Oocyte Meiosis Pathway [NCIt concept]
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
- Salivary Secretion Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Binding [NCIt concept]
- Calcium Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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