Tyrosine-Protein Kinase Transmembrane Receptor ROR2

Preferred Label : Tyrosine-Protein Kinase Transmembrane Receptor ROR2;

NCIt synonyms : NTRKR2; BDB; Neurotrophic Tyrosine Kinase Receptor-Related 2; ROR2; BDB1; Receptor Tyrosine Kinase-Like Orphan Receptor-2; Receptor Tyrosine Kinase-Like Orphan Receptor 2; Neurotrophic Tyrosine Kinase, Receptor-Related 2; EC 2.7.10.1;

NCIt definition : Tyrosine-protein kinase transmembrane receptor ROR2 (937 aa, 105 kDa) is encoded by the human ROR2 gene. This protein is involved in both cartilage formation and receptor signaling.;

Details

Origin ID

C29880;

UMLS CUI

C0211526;

Currated CISMeF NLP mapping
- receptor tyrosine kinase-like orphan receptor 2 [MeSH concept]
OMIM relation
- Receptor tyrosine kinase-like orphan receptor 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- ROR2 protein, human [MeSH concept]
- ROR2 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Kinase Family Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- ROR2 Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Receptor Tyrosine Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Kinase [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Cytoplasmic Domain [NCIt concept]
- Extracellular Domain [NCIt concept]
- Frizzled Domain [NCIt concept]
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Kringle Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
- Tyrosine Kinase Domain [NCIt concept]
gene_product_is_element_in_pathway
- Noncanonical Wnt Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Migration Induction [NCIt concept]
- Cell Proliferation [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]
is_target
- Ozuriftamab Vedotin [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients