Gamma-Aminobutyric Acid Receptor Subunit Alpha-3

Preferred Label : Gamma-Aminobutyric Acid Receptor Subunit Alpha-3;

NCIt synonyms : GABA(A) Receptor Subunit Alpha-3; GABA(A) Receptor, Alpha 3; GABRA3;

NCIt definition : Gamma-aminobutyric acid receptor subunit alpha-3 (492 aa, 55 kDa) is encoded by the human GABRA3 gene. This protein is involved in both ligand-gated chloride transport and the inhibition of neurotransmission.;

NCI Metathesaurus CUI : CL505096;

Details

Origin ID

C126545;

UMLS CUI

C2714738;

Automatic exact mappings (from CISMeF team)
- gamma-aminobutyric acid type A receptor subunit alpha3 [ORDO Gene]
OMIM relation
- Gamma-aminobutyric acid receptor, alpha-3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- GABRA3 protein, human [MeSH Supplementary Concept]
- GABRA3 protein, human [MeSH concept]
gene_encodes_gene_product
- GABRA3 Gene [NCIt concept]
- Ion Channel Protein Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Gated Ion Channel [NCIt concept]
- Ion Channel [NCIt concept]
- Postsynaptic Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Flumazenil Cardioprotection Pathway [NCIt concept]
- GABA Receptor Life Cycle Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Neuronal Transmission [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients