Calcium-Transporting ATPase Type 2C Member 1

Preferred Label : Calcium-Transporting ATPase Type 2C Member 1;

NCIt synonyms : EC 7.2.2.10; Ca(2 )/Mn(2 )-ATPase 2C1; SPCA1; ATPase 2C1; ATP2C1; Secretory Pathway Ca(2 )-Transporting ATPase Type 1; ATP-Dependent Ca(2 ) Pump PMR1;

NCIt definition : Calcium-transporting ATPase type 2C member 1 (919 aa, 101 kDa) is encoded by the human ATP2C1 gene. This protein is involved in ATP-dependent transport of Ca2 and Mn2 that modulates the secretory pathway.;

NCIt note : Calcium-transporting ATPase type 2C member 1 is expressed as at least 9 isoforms due to alternatively splicing; most fall into two major categories, ATP2C1A and ATP2C1B. The A and B isoforms have different C-terminal sequences but are expressed in the same tissues. (OMIM and UniProt);

Détails

Origin ID

C215317;

OMIM relation
- Atpase, ca(2+)-transporting, type 2c, member 1 [OMIM gene]
gene_encodes_gene_product
- ATP2C1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Translocase Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Membrane of the Golgi Apparatus [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- ATP Hydrolysis [NCIt concept]
- Calcium Binding [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

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