T-Lymphocyte Activation Antigen CD86

Preferred Label : T-Lymphocyte Activation Antigen CD86;

NCIt synonyms : B70; FUN-1; Activation B7-2 Antigen; CTLA-4 Counter-Receptor B7.2; BU63; CD86 Antigen; B72 Antigen; B-Lymphocyte Antigen B7.2; B-Lymphocyte Activation Antigen B7-2; CD28 Antigen Ligand 2;

NCIt definition : T-lymphocyte activation antigen CD86 (329 aa, 38 kDa) is encoded by the human CD86 gene. This protein plays a role in signal transduction that mediates T-cell proliferation and interleukin gene transcription.;

Details

Origin ID

C78147;

UMLS CUI

C2700434;

Currated CISMeF NLP mapping
- B7-2 Antigen [MeSH Descriptor]
- B7-2 Antigen [MeSH concept]
OMIM relation
- Cd86 antigen [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CD86 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Activated B-Lymphocyte [NCIt concept]
- Monocyte [NCIt concept]
gene_product_has_biochemical_function
- CTLA-4 Ligand [NCIt concept]
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Immunoglobulin-Like V-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Allograft Rejection Pathway [NCIt concept]
- Autoimmune Thyroid Disease Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Graft-Versus-Host Disease Pathway [NCIt concept]
- IL12/STAT4 Signaling Pathway [NCIt concept]
- Intestinal IgA Production Pathway [NCIt concept]
- Systemic Lupus Erythematosus Pathway [NCIt concept]
- T-Cell Activation Co-Stimulatory Signaling Pathway [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Th1/Th2 Differentiation Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
- Type I Diabetes Mellitus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune Response Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- T-Cell Proliferation [NCIt concept]

Keyword's position in hierarchy(ies) :

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