Intercellular Adhesion Molecule 4

Preferred Label : Intercellular Adhesion Molecule 4;

NCIt synonyms : ICAM-4; ICAM4; CD242; CD242 Antigen; Landsteiner-Wiener Blood Group Glycoprotein; LW Blood Group Protein;

NCIt definition : Intercellular adhesion molecule 4 (271 aa, 29 kDa) is encoded by the human ICAM4 gene. This protein is involved in integrin binding and cell-cell adhesion.;

NCIt note : The molecular basis of the Landsteiner-Wiener (LW) blood group antigens is a single amino acid variation at position 100 of the intercellular adhesion molecule 4 protein; a glutamine at this position is the LW(A) blood group and arginine is the LW(B) blood group. (EntrezGene and OMIM);

Details

Origin ID

C189999;

UMLS CUI

C1456805;

Automatic exact mappings (from CISMeF team)
- Intracellular adhesion molecule 4 [OMIM gene]
OMIM relation
- Intracellular adhesion molecule 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- ICAM4 protein, human [MeSH Supplementary Concept]
- ICAM4 protein, human [MeSH concept]
gene_encodes_gene_product
- Cell Adhesion Molecule Gene [NCIt concept]
- ICAM4 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Erythrocyte [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Glycoprotein [NCIt concept]
- Immunoglobulin Family Protein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Lymphocyte Adhesion Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Immune Response Process [NCIt concept]
- Ligand Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

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