RNA-Binding Protein 8A

Preferred Label : RNA-Binding Protein 8A;

NCIt synonyms : RNA Binding Motif Protein 8A; Ribonucleoprotein RBM8; RNA-Binding Motif Protein 8A; RNA-Binding Protein Y14; RNA Binding Protein 8A; Binder of OVCA1-1; RBM8A; RNA-Binding Motif Protein 8; Ribonucleoprotein RBM8A;

NCIt definition : RNA-binding protein 8A (174 aa, 20 kDa) is encoded by the human RBM8A gene. This protein is involved in exon junction complex formation and the regulation of mRNA splicing.;

NCIt note : RNA-binding protein 8A may also inhibit formation of proapoptotic forms of BLC2L1 and other apoptosis regulatory genes through the modulation of splicing that is separate from the activity RNA-binding protein 8A takes part in as a member of the exon junction complex. (UniProt);

Details

Origin ID

C177191;

UMLS CUI

C5444598;

Automatic exact mappings (from CISMeF team)
- RNA binding motif protein 8A [HGNC gene]
- RNA binding motif protein 8A [ORDO Gene]
- Rna-binding motif protein 8a [OMIM gene]
OMIM relation
- Rna-binding motif protein 8a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- RBM8A Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- RNA Recognition Motif [NCIt concept]
gene_product_is_element_in_pathway
- Spliceosome Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Nonsense-Mediated Decay [NCIt concept]
- RNA Binding [NCIt concept]
- RNA Splicing [NCIt concept]
- mRNA Export [NCIt concept]

Keyword's position in hierarchy(ies) :

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