" /> Toll-Like Receptor 1 - CISMeF





Preferred Label : Toll-Like Receptor 1;

NCIt synonyms : TIL; Toll/Interleukin-1 Receptor-Like; TLR1; Toll-Like Receptor-1; CD281 Antigen; Toll/Interleukin-1 Receptor-Like Protein;

NCIt definition : Toll-like receptor 1 (786 aa, 90 kDa) is encoded by the human TLR1 gene. This protein plays a role in antimicrobial immune responses.;

NCIt note : Toll-like receptor (TLR) 1 binds to the TLR2 extracellular domain and cooperates with TLR2 to regulate lipoprotein-dependent inate immunity. TLR1 appears to bind MyD88 via their TIR domains, and to TRAF6, leading to NF-Kappa-B activation, cytokine secretion, and inflammatory responses.;

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29/07/2025


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