Scavenger Receptor Cysteine-Rich Type 1 Protein M130

Preferred Label : Scavenger Receptor Cysteine-Rich Type 1 Protein M130;

NCIt synonyms : CD163 Molecule; Macrophage-Associated Antigen; Hemoglobin Scavenger Receptor; CD163; CD163 Antigen; Antigen CD163;

NCIt definition : Scavenger receptor cysteine-rich type 1 protein M130 (1156 aa, 125 kDa) is encoded by the human CD163 gene. This protein plays a role in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages.;

Details

Origin ID

C104064;

UMLS CUI

C1570089;

OMIM relation
- Cd163 antigen [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- CD163 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CD163 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Intracellular Membrane [NCIt concept]
- Macrophage [NCIt concept]
- Monocyte [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Scavenger Receptor Cysteine-Rich Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Receptor Mediated Endocytosis [NCIt concept]
- Receptor Signaling [NCIt concept]
is_target
- Anti-CD163 Monoclonal Antibody OR2805 [NCIt concept]

Keyword's position in hierarchy(ies) :

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