CD166 Antigen - CISMeF

Preferred Label : CD166 Antigen;

NCIt synonyms : CD6 Ligand; BEN; Activated Leukocyte Cell Adhesion Molecule; Neurolin; ALCAM; CD6L;

NCIt definition : CD166 antigen (583 aa, 65 kDa) is encoded by the human ALCAM gene. This protein is involved in cell adhesion.;

NCIt note : Cell adhesion molecule expressed on activated leukocytes, fibroblasts, and neurons. It is a ligand for CD6. ALCAM-CD6 interactions may play a role in the binding of T and B cells to activated leukocytes.;

Details

Origin ID

C17920;

UMLS CUI

C0538294;

Currated CISMeF NLP mapping
- Activated-Leukocyte Cell Adhesion Molecule [MeSH concept]
- Activated-Leukocyte cell adhesion molecule [MeSH Descriptor]
- neurolin [MeSH concept]
False automatic mappings
- Danubian endemic familial nephropathy [OMIM Phenotype]
OMIM relation
- Activated leukocyte cell adhesion molecule [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- ALCAM protein, human [MeSH concept]
- ALCAM protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ALCAM Gene [NCIt concept]
- Cell Adhesion Molecule Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Fibroblast [NCIt concept]
- Leukocyte [NCIt concept]
- Neuron [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Immunoglobulin Family Protein [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Immunoglobulin-Like V-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
is_target
- Praluzatamab Ravtansine [NCIt concept]

Keyword's position in hierarchy(ies) :

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