Low Affinity Immunoglobulin Gamma Fc Region Receptor II-B

Preferred Label : Low Affinity Immunoglobulin Gamma Fc Region Receptor II-B;

NCIt synonyms : Fc-Gamma RIIB; CD32 Antigen; FCGR2; Low Affinity Immunoglobulin Gamma Fc Region Receptor IIB; FcRIIB; IGFR2; Fc-Gamma-RIIB; Low Affinity IgG Fc Fragment Receptor IIB; FCG2; CD32; FCGR2B; IgG-Fc-Receptor-IIB; IgG Fc Receptor II-B; FcRII-b; Fc-Gamma RII-B; IgG Fc Receptor IIB; CD32b;

NCIt definition : Low affinity immunoglobulin gamma Fc region receptor II-b (310 aa, 34 kDa) is encoded by the human FCGR2B gene. This protein is involved in the phagocytosis of opsonized antigens.;

Details

Origin ID

C38555;

UMLS CUI

C1452607;

Currated CISMeF NLP mapping
- CD32 antigens [MeSH concept]
OMIM relation
- Fc fragment of igg receptor iib [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- FCGR2B protein, human [MeSH concept]
- FCGR2B protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- FCGR2B Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Fc-Gamma Receptor II [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Immunoreceptor Tyrosine-Based Motif [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- B Cell Receptor Signaling Pathway [NCIt concept]
- BCR Immune Response Signaling Pathway [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- B-Cell Activation [NCIt concept]
- Immune Response Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Phagocytosis [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- T-Cell Activation [NCIt concept]
is_target
- Anti-CD32B Monoclonal Antibody BI-1206 [NCIt concept]

Keyword's position in hierarchy(ies) :

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