" /> Lysosomal Cobalamin Transport Escort Protein LMBD1 - CISMeF





Preferred Label : Lysosomal Cobalamin Transport Escort Protein LMBD1;

NCIt synonyms : LMBD1; Hepatitis Delta Antigen-L Interacting Protein; LMBR1 Domain Containing 1; Nuclear Export Signal-Interacting Protein; NES-Interacting Protein; LMBRD1; Liver Regeneration P-53 Related Protein; HDAg-L-Interacting Protein NESI; LMBR1 Domain-Containing Protein 1;

NCIt definition : Lysosomal cobalamin transport escort protein LMBD1 (540 aa, 61 kDa) is encoded by the human LMBRD1 gene. This protein plays a role in vitamin B12 transport from the lysosome into the cytoplasm.;

NCIt note : Lysosomal cobalamin transport escort protein LMBD1 associates with lysosomal cobalamin transport protein ABCD4, induces the translocation of ABCD4 from the endoplasmic reticulum to the lysosome. This heterodimer binds to cyanocobalamin reductase / alkylcobalamin dealkylase (MMACHC) in the lysosome. The trimeric complex mediates the transport of cobalamin from the lysosome to the cytoplasm. (UniProt);

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18/05/2024


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