Nuclear Receptor ROR-Gamma T

Preferred Label : Nuclear Receptor ROR-Gamma T;

NCIt synonyms : Retinoic Acid-Binding Receptor Gamma Isoform 2; Nuclear Receptor RZR-Gamma Isoform 2; Nuclear Receptor Subfamily 1 Group F Member 3 Isoform 2; RORgammaT; RORgT; Retinoic Acid-Related Orphan Receptor Gamma T; Retinoid-Related Orphan Receptor Gamma Isoform 2; Nuclear Receptor ROR-Gamma Isoform 2; Nuclear Receptor RORgamma(t); Nuclear Receptor ROR Gamma T; Retinoid-Related Orphan Receptor-Gamma Isoform 2;

NCIt definition : Nuclear receptor ROR-gamma T (497 aa, 56 kDa) is encoded by the human RORC gene. This protein is involved in both ligand-dependent transcriptional regulation and the differentiation of helper T-cells.;

NCI Metathesaurus CUI : CL1663275;

Details

Origin ID

C106314;

UMLS CUI

C2715150;

Automatic exact mappings (from CISMeF team)
- nuclear receptor subfamily 1, group F, member 3 [MeSH Descriptor]
OMIM relation
- Rar-related orphan receptor C [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- RORC protein, human [MeSH Supplementary Concept]
- RORC protein, human [MeSH concept]
- orphan nuclear receptor ROR-gammaT [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- Nuclear Receptor Gene [NCIt concept]
- RORC Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
- Thymocyte [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Hormone Receptor [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Nuclear Hormone Receptor Superfamily [NCIt concept]
gene_product_has_structural_domain_or_motif
- Hormone Receptor DNA-Binding Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- DNA Binding [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Maturation [NCIt concept]
- Pattern Formation [NCIt concept]
- Receptor Signaling [NCIt concept]
- T-Cell Differentiation [NCIt concept]
- Transcription Initiation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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