Preferred Label : Natural Killer Cells Antigen CD94;
NCIt synonyms : KLRD1; Killer Cell Lectin-Like Receptor Subfamily D, Member 1 Isoforms 1, 2; KLRD1 Protein; Killer Cell Lectin-Like Receptor Subfamily D, Member 1 Protein; Natural Killer Cell Antigen CD94; Killer Cell Lectin-Like Receptor Subfamily D, Member 1; KP43; NK Cell Receptor; CD94 Antigen; CD94; Killer Cell Lectin-Like Receptor Subfamily D Member 1;
NCIt definition : Natural killer cells antigen CD94 (179 aa, 20 kDa) is encoded by the human KLRD1
gene. This protein is involved in signaling in natural killer cells.;
NCIt note : Preferentially expressed in NK lymphocytes, CD94 Antigen (179-amino acid, 20.5-kD
CD94-A and 148-amino acid CD94 ALT) is encoded by KLRD1 Gene (C-Lectin Family) and
may regulate NK cell function. A type II membrane protein (external C-terminus), CD94
contains a 147-amino acid extracellular domain with C-type lectin motifs, a 26-amino
acid transmembrane domain, and a 7-amino acid cytoplasmic domain (absent in CD94 ALT).
CD94 forms disulfide-bonded heterodimers with NKG2A, NKG2C, and NKG2E. Nonclassical
MHC HLA-E protein ligand binds to CD94/NKG2A, CD94/NKG2B, and CD94/NKG2C NK cell receptors.;
Origin ID : C26478;
UMLS CUI : C1506359;
Currated CISMeF NLP mapping
- OMIM relation
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- gene_encodes_gene_product
- gene_product_expressed_in_tissue
- gene_product_has_associated_anatomy
- gene_product_has_biochemical_function
- gene_product_has_chemical_classification
- gene_product_has_organism_source
- gene_product_has_structural_domain_or_motif
- gene_product_is_element_in_pathway
- gene_product_plays_role_in_biological_process
