Ephrin-B2 - CISMeF

Preferred Label : Ephrin-B2;

NCIt synonyms : EPH-Related Receptor Tyrosine Kinase Ligand 5; HTK Ligand; Ligand of Eph-Related Kinase 5; LERK-5; HTK-L; EFNB2;

NCIt definition : Ephrin-B2 (333 aa, 37 kDa) is encoded by the human EFNB2 gene. This protein is involved in cell-cell communication.;

NCIt note : The signaling pathways downstream of ephrin receptors are referred to as forward signaling while the signaling pathways downstream of the ephrin ligands are referred to as reverse signaling. (UniProt);

Details

Origin ID

C105843;

UMLS CUI

C3810534;

Automatic exact mappings (from CISMeF team)
- Ephrin b2 [OMIM gene]
- ephrin B2 [HGNC gene]
Currated CISMeF NLP mapping
- Ephrin-B2 [MeSH concept]
- ephrin-b2 [MeSH Descriptor]
OMIM relation
- Ephrin b2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- EFNB2 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Axon Guidance Pathway [NCIt concept]
- Ephrin B Forward Signaling Pathway [NCIt concept]
- Ephrin B Reverse Signaling Pathway [NCIt concept]
- Ephrin B Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell-Cell Adhesion Process [NCIt concept]
- Chemotactic Process [NCIt concept]
- Intercellular Communication Induction [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
is_target
- Recombinant EphB4-HSA Fusion Protein [NCIt concept]

Keyword's position in hierarchy(ies) :

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