APOBEC1 Complementation Factor

Preferred Label : APOBEC1 Complementation Factor;

NCIt synonyms : A1CF; Apo-B RNA Editing Protein; APOBEC-1 Stimulating Protein; APOBEC1-Stimulating Protein;

NCIt definition : APOBEC1 complementation factor (594 aa, 65 kDa) is encoded by the human A1CF gene. This protein is involved in binding to and metabolism of APOB mRNA. Missense mutations in the gene may be associated with melanoma and other neoplastic diseases.;

NCIt note : APOBEC1 complementation factor may be responsible for docking the catalytic APOBEC1 complex with APOB mRNA.;

Details

Origin ID

C143033;

UMLS CUI

C0104364;

Automatic exact mappings (from CISMeF team)
- APOBEC1 complementation factor [HGNC gene]
- Apobec1 complementation factor [OMIM gene]
OMIM relation
- Apobec1 complementation factor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- A1CF protein, human [MeSH Supplementary Concept]
- A1CF protein, human [MeSH concept]
gene_encodes_gene_product
- A1CF Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Heterochromatin [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- RNA Recognition Motif [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- RNA Binding [NCIt concept]
- RNA Processing [NCIt concept]

Keyword's position in hierarchy(ies) :

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