Advanced Glycosylation End Product-Specific Receptor

Preferred Label : Advanced Glycosylation End Product-Specific Receptor;

NCIt synonyms : AGER; Receptor For Advanced Glycosylation End Products; RAGE;

NCIt definition : Advanced glycosylation end product-specific receptor (404 aa, 43 kDa) is encoded by the human AGER gene. This protein is involved in advanced glycation end product binding, inflammatory responses and receptor-mediated signaling.;

Details

Origin ID

C106214;

UMLS CUI

C3812151;

Automatic exact mappings (from CISMeF team)
- Advanced glycosylation end product-specific receptor [OMIM gene]
- Mok protein kinase [OMIM gene]
- Rabies [ORDO Disease]
- Rabies [UNVA Disease]
- Rage [MedDRA LLT]
- Receptor for Advanced Glycation End Products [MeSH concept]
- Receptor for Advanced Glycation End Products [MeSH Descriptor]
- rage [MeSH Descriptor]
- rage [MeSH concept]
OMIM relation
- Advanced glycosylation end product-specific receptor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- AGER protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- AGER Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Immunoglobulin-Like V-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- AlphaM/Beta2 Integrin Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune Response Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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