Endoplasmic Reticulum Export Factor CTAGE5

Preferred Label : Endoplasmic Reticulum Export Factor CTAGE5;

NCIt synonyms : CTAGE Family Member 5 ER Export Factor; CTAGE5; Protein cTAGE-5; Cutaneous T-Cell Lymphoma-Associated Antigen 5; Meningioma-Expressed Antigen 6/11;

NCIt related terms : cTAGE Family Member 5;

NCIt definition : Endoplasmic reticulum export factor CTAGE5 (804 aa, 91 kDa) is encoded by the human CTAGE5 gene. This protein is involved in intracellular protein transport and tumor induced immune responses.;

NCIt note : Endoplasmic reticulum export factor CTAGE5 is required for intracellular transport and secretion of collagen VII (COL7A1) . (UniProt); It is not clear whether the MIA2/CTAGE5 locus is comprised of one gene or two distinct genes. HGNC, EntrezGene and OMIM consider this locus to be part of the MIA2 gene (HGNC:18432). However, UniProt has separate entries for the protein products of the melanoma inhibitory activity 2-specific transcripts and cTAGE family member 5-specific transcripts.;

Details

Origin ID

C114659;

UMLS CUI

C1431063;

Automatic exact mappings (from CISMeF team)
- Mia sh3 domain er export factor 2 [OMIM gene]
OMIM relation
- Mia sh3 domain er export factor 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- MIA2 protein, human [MeSH Supplementary Concept]
- MIA2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CTAGE5 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Proline-Rich Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Protein Secretion [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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