Glycine Receptor Subunit Alpha-1

Preferred Label : Glycine Receptor Subunit Alpha-1;

NCIt synonyms : Glycine Receptor Strychnine-Binding Subunit; Glycine Receptor Alpha 1; Glycine Receptor Subunit Alpha 1; Glycine Receptor 48 kDa Subunit;

NCIt related terms : GlyRa1; Glycine Glycine Receptor 48 kDa Subunit; GLRA1;

NCIt definition : Glycine receptor subunit alpha-1 (457 aa, 53 kDa) is encoded by the human GLRA1 gene. This protein is involved in ligand-gated chloride ion transport.;

Alternative definition : CDISC: An antigen encoded by the GLRA1 gene and the alpha helical transmembrane subunit of the glycine receptor. It can be considered as an autoantigen and is commonly associated with the autoimmune neurological disorder stiff-person syndrome.;

Details

Origin ID

C207239;

OMIM relation
- Glycine receptor, alpha-1 subunit [OMIM gene]
concept_is_in_subset
- CDISC SDTM Binding Agent for Immunogenicity Tests Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
gene_encodes_gene_product
- GLRA1 Gene [NCIt concept]
- Ion Channel Protein Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Gated Ion Channel [NCIt concept]
- Ion Channel [NCIt concept]
- Synapse [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_product_is_physical_part_of
- Glycine Receptor Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- Glycine Receptor Binding [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Muscle Contraction [NCIt concept]
- Neuronal Transmission [NCIt concept]
- Receptor Signaling [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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