Hepatitis A Virus Cellular Receptor 2

Preferred Label : Hepatitis A Virus Cellular Receptor 2;

NCIt synonyms : T-Cell Membrane Protein 3; T-Cell Immunoglobulin And Mucin Domain-Containing Protein 3; T Cell Immunoglobulin Mucin-3; HAVcr-2; HAVCR2; TIMD-3; T Cell Immunoglobulin Mucin 3; TIM-3; Kidney Injury Molecule-3; CD366 Antigen; CD366;

NCIt definition : Hepatitis A virus cellular receptor 2 (301 aa, 33 kDa) is encoded by the human HAVCR2 gene. This protein plays a role in the regulation of T helper cell and macrophage activation.;

Details

Origin ID

C104278;

UMLS CUI

C1120826;

Currated CISMeF NLP mapping
- Hepatitis A Virus Cellular Receptor 2 [MeSH Descriptor]
OMIM relation
- Hepatitis a virus cellular receptor 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- HAVCR2 protein, human [MeSH Supplementary Concept]
- HAVCR2 protein, human [MeSH concept]
- Hepatitis A Virus Cellular Receptor 2 [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- HAVCR2 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_expressed_in_tissue
- Type 1 Helper Cell [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Immunoglobulin Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like V-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Immunologic Tolerance [NCIt concept]
- Ligand Binding [NCIt concept]
- Myeloid Cell Activation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- T-Cell Activation [NCIt concept]
is_target
- Anti-PD-1/Anti-TIM-3 Bispecific Antibody AZD7789 [NCIt concept]
- Anti-PD-1/Anti-TIM-3 Bispecific Antibody LB1410 [NCIt concept]
- Anti-TIM-3 Antibody BMS-986258 [NCIt concept]
- Anti-TIM-3 Monoclonal Antibody BC3402 [NCIt concept]
- Anti-TIM-3 Monoclonal Antibody Sym023 [NCIt concept]
- Anti-TIM-3 Monoclonal Antibody TQB2618 [NCIt concept]
- Anti-TIM3 Monoclonal Antibody LY3321367 [NCIt concept]
- Autologous Anti-TIM-3/Anti-CD123 CAR T-cells [NCIt concept]
- Cobolimab [NCIt concept]
- Sabatolimab [NCIt concept]
- Surzebiclimab [NCIt concept]
- Verzistobart [NCIt concept]

Keyword's position in hierarchy(ies) :

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